NSC 304 - Receptors & Channels

Course unit(s): 1
Meets requirement: W
Prerequisite(s): NSC 301 Neurons & Networks or BIO 220 Biochemistry or permission of instructor.
A critical discussion of the structural and physiological principles of neurotransmitter receptor and ion channel signaling. Course lectures will introduce the foundational theories and methods of molecular pharmacology, biophysics, and structural biology. Topics discussed will include structural determinations of membrane proteins; receptor-ligand interactions; allosteric signaling of receptors; channel kinetics; and protein-protein signaling associations. Relevant primary literature will be introduced through class discussions and independent critical analyses.