1 course unit A laboratory based course concerned with modern experimentation in biochemistry. In the first module students use recombinant DNA technology to overexpress an enzyme, then purify and characterize it. Theory and biochemical context is discussed throughout. The second module covers modern biochemical experimentation, including mass spectrometry of proteins and proteomic methods for analysis of cell states. Students also design and execute an original research project. Four hours laboratory and two hours of lecture per week. Prerequisite(s):CHM 202 Organic Chemistry II or CHM 204, 206 Organic Chemistry IIA. Meets general academic requirement W.